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Laboratory Medicine Grand Rounds

Description:
The primary purpose of Laboratory Medicine Grand Rounds is to provide up-to-date information on laboratory testing for diagnosis, prognosis, and monitoring diseases. The series covers test ordering and interpretation as well as issues related to quality improvement in clinical laboratory services. The course also encompasses current research and trends in laboratory medicine and in medicine more generally, and how these are likely to impact the future practice of medicine. Lastly, the course includes lectures on general topics in medicine that provide up-to-date information in areas where laboratory testing is of particular importance.

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Programs in this series:

Advances in Cervical Cancer - Laura Koutsky, Ph.D., MSPH
Dr. Laura Koutsky discusses the advances in cervical cancer care.

Advances in Understanding Susceptibility to Infectious Diseases - Thomas Hawn, MD, Ph.D.
Recent advances in innate immunity, genetics, and infectious diseases.

Assessing Competency in Health Care Workers: Can We Assess Ourselves? How Can We Assess Others? - Dave Davis, MD
Assessment of health professional competence and performance.

Assessing Prenatal Risk: Current State of the Art - Dr. Edith Chang
This presentation summarizes the history and evolution of prenatal diagnosis.

Beyond ROC Curves: Recent Statistical Advances in the Evaluation of Diagnostic and Prognostic Tests - Dr. Amalia Magaret
Learn about adaptations to standard ROC curves with consideration to cost, predictors of disease, and comparison and combination of predictive markers.

Biomarkers and Early Cancer Detection - Peter Nelson, MD
Scientific advances producing potential new biomarkers for the early detection of cancer and improved disease management.

Combing the Evidence for Support of Lab-based Screening Tests: An Update From the US Preventive Services Task Force - David Grossman, MD, MPH
US Preventive Services Task force use of evidence-based approaches.

Detecting Circulating Tumor Cells - Dr. Daniel Sabath
Explores detecting minimal residual disease in cancer therapy.

Disclosing Harmful Medical Errors to Patients: What Is the Data Telling Us? - Thomas Gallagher, MD
Recent developments related to the disclosure of harmful medical errors to patients.

Early Detection and Prognosis for Ovarian Cancer - Elizabeth Swisher, MD
Current and future technologies for ovarian cancer screening are discussed.

Engraftment Monitoring Following Human Stem Cell Transplantation - Shalini Pereira, Ph.D.
New testing technology identifies genetic profiles after stem cell transplants.

Experience and Problems in Laboratory Medicine in Developing Countries - Jack H. Ladenson, Ph.D.
This lecture discusses upgrading clinical laboratories and training in developing countries.

From Lab Medicine Resident to Pharmaceutical CEO: The Story of Syntrix Biosystems - John Zebala, MD, Ph.D.

Harnessing the Power of Next-Generation DNA Sequencing - Jay Shendure, MD, PhD
University of Washington researcher Jay Shendure discusses next-generation DNA sequencing.

HIV-1 Infection: Laboratory Diagnosis and Utility of Rapid Testing - A Tiresian Odyssey - Robert Coombs, MD, PhD
Learn about HIV diagnostic algorithms from the University of Washington.

HSV As A Successful Pathogen: The Quest for Developing A Vaccine - Dr. Lawrence Corey

Immunopathogenesis and Epidemiology of Malaria - Patrick Duffy, MD

Improving Lab Utilization in Ambulatory Care: The Role of Physician - Kim Riddell, MD
Choosing appropriate tests.

International Medicine: What Do Developing Countries Need? - King Holmes, MD, Ph.D.
Learn how clinical and public health laboratories play a central role in preserving global health.

Is There a Role for Laboratory Testing in Pain Medicine? or How to Objectify the Subjective? - Alex Cahana, MD
Is there a way to explore the subjectivity of pain?

Laboratory Diagnosis of Bacterial and Fungal Diseases - Brad Cookson, MD, Ph.D.
Molecular biology in medicine.

Laboratory Medicine: Back to the Future - James Fine, MD
Laboratory medicine plays an increasingly major role in clinical care.

Laboratory Testing Needs in Developing Countries - Matthew Steele, Ph.D., M.P.H.
Efforts by Seattle-based PATH (Program for Appropriate Technology in Health) to develop diagnostic tests targeted for use in third-world countries with limited resources.

Lymphoproliferative Disorders Following Solid Organ Transplant - Virginia Broudy, MD
Risk of lymphoma in patients who received an organ transplant.

Medical Applications of Array CGH and the Transformation of Clinical Cytogenetics - Bassem Bejjani, MD
This talk will describe the methodology of array CGH.

Medical Errors and Patient Safety in the Clinical Lab - Kaveh Shojania, MD
A discussion of the international patient safety movement.

Microarrays for the Detection of Chromosomal Anomalies - Dr. Karen Tsuchiya
The introduction of array-based comparative genomic hybridization (aCGH) is revolutionizing the field of cytogenetics.

Molecular Assays for Colorectal Cancer Care - William Grady, MD
Molecular assays for colorectal cancer will be reviewed.

Molecular Testing in Breast Cancer: Will it Become Standard Practice? - Kimberly Allison, MD
Research using gene expression signatures to identify subtypes of breast cancer.

MRSA - The Bug Stops Here - Ferric Fang, MD
This lecture reviews detection, prevention and treatment of MRSA infections.

Neurogenetics of Huntington’s Disease - Albert La Spada, MD Ph.D.
How and why neurons die in Huntington's disease and spinocerebellar ataxia type 7.

New Developments in Syphilis and HIV Testing - Matthew Golden, MD

Novel Ways to Construct and Use Nanoscale Devices for Biochemical Analysis - Babak Parviz, Ph.D.
Direct nano-scale electronic detection of biomarkers and construction of low-cost disposable biosensors.

Pharmacogenomic Testing and Breast Cancer: The Example of Cyp2D6 and Tamoxifen - Dr. Hannah Linden
Recent laboratory and clinical trial evidence regarding tamoxifen metabolism and the impact of CYP2D6 pharacogenomic profiling.

Point of Care Diagnostics for the Developing World - Paul Yager, Ph.D.
Learn about a project is to develop an inexpensive system that can bring sophisticated modern medical diagnostic lab techniques to those in need.

Postanalytic Error: Cases, Concepts and Interventions - Michael Astion, MD, Ph.D.
Reducing laboratory errors.

Quality and Efficiency Solutions for Anatomic Pathology - Rodney Schmidt, MD
The University of Washington is improving anatomic pathology lab work.

Real-Time Continuous Glucose Monitoring: Revolutionary or Another Fad? - Irl Hirsch, MD
University of Washington researcher Irl Hirsch asks: Is real-time continuous glucose monitoring a reliable solution for managing diabetes, or just another fad?

Stem Cell Therapy in Cardiac Disease - Charles Murry, MD, Ph.D.
Stem cells to repair the heart or other damaged organs.

Storage Lesions in Cellular Blood Components - James AuBuchon, MD
Examine the effectiveness of old blood in this video from the University of Washington.

The Antiphospholipid Syndrome - Dr. Michael Linenberger
Dr. Linenberger discusses the effects of antiphospholipid syndrome, how the pathological antibodies might cause problems, and the various treatment approaches when vascular or pregnancy complications occur.

The Diagnosis Tipping Point: To Change or Not to Change? - Brian Budenholzer, MD
How doctors decide to embrace the new and abandon the old way.

The Jekyll and Hyde of Regulatory Issues: Effects on the Evidence-Based Medicine of Laboratory Tests - Larry Kessler, Sc.D.
Dr. Kessler describes the US Food and Drug Administration’s approach to classification of in vitro diagnostic devices.

The Promise and Perils of Herbal Remedies - Chihiro Morishima, MD
The University of Washington’s Dr. Chihiro Morishima discusses the promises and perils of herbal remedies.

The Promise of Plasma Proteomics in the Clinical Laboratory: Fact and Fiction - N. Leigh Anderson, Ph.D.
Mass spectrometry could one day help measure proteins in the routine clinical laboratory.

The Role of Nanotechnology in the Clinical Laboratory - Steven C. Kazmierczak, Ph.D.
This lecture provides an understanding of the concepts underlying nanotechnology.

The Use and Misuse of Laboratory Tests for Nutritional Status - Edward Lipkin, MD, PhD
From the University of Washington, a look at the laboratory evaluation of nutritional status.

Total Laboratory Automation - Michael Bissell, MD, Ph.D.

Trends in Autoantibody Testing - Mark H. Wener, MD
Testing for such conditions as Lupus, Rheumatoid Arthritis, and other autoimmune diseases.

Trends in Multiparameter Flow Cytometry in Hematology - Dr. Brent Wood

Trends in Newborn Screening - Michael Glass, MS
The latest trends in what tests to give to newborns and outcome for them as children.

Trends in the Clinical Laboratory Industry - Dr. Thomas Tiffany

Understanding the Appropriate Use of Lipid Testing - John Brunzell, MD
Dr. John Brunzell discusses issues related to measurement of lipoprotein subfractions.

Update on Markers for Cardiovascular Disease Risk - Kevin O'Brien, MD
Learn how to identify the risk of cardiovascular disease.

An Update on Fibromyalgia

Inside Stories: Milton Masciadri

Building a Community-based Health Care Movement

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